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CLINICAL EVIDENCE

PROVEN BY SCIENCE.
TRUSTED WORLDWIDE.

A growing body of independent clinical research confirms the safety, effectiveness, and patient preference of the NeedleFree injection system.

Independent Clinical Studies

Multiple peer-reviewed studies have evaluated NeedleFree across a wide range of medications and populations.
Click on any study below to read the full research.

Needleless Injectors for the Administration of Vaccines: A Review of Clinical Effectiveness View Study Human Vaccines & Immunotherapeutics 2015
Needle-Free Injections in Dentistry View Study The Journal of the American Dental Association 2016
Needle-Free Injection Solution for Podiatrists View Study Journal of the American Podiatric Medical Association 2016
Clinical Studies With Jet Injection View Study Journal of Diabetes Science and Technology 2017
Improved Pharmacokinetic and Pharmacodynamic Profile of Rapid Acting Insulin Using Needle Free Injection Technology View Study Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2018
Jet Injector in Diabetes for Early Post Prandial Glucose Control View Study Diabetes Technology & Therapeutics 2018
B-12 Intramuscular vs. Subcutaneous Injection View Study American Family Physician 2019
Zika Virus Needle Free System View Study Expert Review of Vaccines 2019
Brazil Published Journal With Comfort-in View Study Diabetes Technology & Therapeutics 2019
Position Statement on Jet Injectors View Study Diabetes Technology & Therapeutics 2019
Twice Daily Mixed Regular and NPH Insulin Injections With New Jet Injector Versus Conventional Syringes: Pharmacokinetics of Insulin Absorption View Study Diabetes Technology & Therapeutics 2019
A Survey of Patient Preference for Insulin Jet Injectors Versus Needle and Syringe View Study Diabetes Technology & Therapeutics 2020
Comparison of Insulin Levels After Injection by Jet Stream and Disposable Insulin Syringe View Study Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020
Comparison of Plasma Insulin Profiles After Subcutaneous Administration of Insulin by Jet Spray and Conventional Needle Injection in Patients With Insulin Dependent Diabetes Mellitus View Study Diabetes & Metabolism Syndrome: Clinical Research & Reviews 2020
Blood Glucose and Free Insulin Levels After the Administration of Insulin by Conventional Syringe or Jet Injector in Insulin Treated Type 2 Diabetics View Study Journal of Clinical and Diagnostic Research 2020
COVID-19 Vaccine Trial (needle free) View Study Scientia Clinical Research (Clinical Trials System) 2021
Subcutaneous Injection of Testosterone Is an Effective and Preferred Alternative to Intramuscular Injection: Demonstration in Female-to-Male Transgender Patients View Study The Journal of Clinical Endocrinology & Metabolism 2021

Backed by Science. Built for Trust.

All studies were conducted in accordance with Good Clinical Practice (GCP) guidelines and published in peer-reviewed journals.